BBS Faculty

 

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z

 

Faculty Name Research Summary
Abzhanov, ArkhatOral Developmental Biology
Ahmad, KamiHistone variants and chromosome biology
Alper, Seth Molecular cellular pathophysiology of ion transport
Alt, Frederick Lymphocyte Differentiation, Recombination, DNA repair, cancer
Altshuler, David Genomic approaches to human disease genetics
Anderson, PaulRNA granules
Arany, ZoltanGene Regulation of Metabolism in Cardiovascular Health and Disease
Arlotta, PaolaMolecular and Developmental Neurobiology
Armstrong, ScottGenomics of Leukemia
Arnaout, M. AminAdhesion, Integrins, hematopoiesis, kidney genetics
Artavanis-Tsakonas, SpyrosMolecular Genetics of Cell Interaction in Development
Aster, JonRole of Notch Signaling in Lymphoid Neoplasia
Ausiello, DennisMembrane Biology
Ausubel, Fred Molecular Biology of Pathogenesis
Avidor-Reiss, TomerCentriole, Centrosome and Cilium: Biogenesis, Function and Evolution
Balk, StevenSteroid Hormone Receptors and Prostate Cancer
Baron, RolandBone cells differentiation, function and signaling
Beckwith, JonathanMicrobiology and Molecular Genetics
Beggs, AlanMolecular genetics of human neuromuscular diseases
Beier, DavidMouse Models of Human Disorders
Bender, WelcomeDrosophila Molecular Genetics
Berliner, NancyMolecular regulation of granulocyte differentiation
Bernhardt, ThomasBacterial cell division and cell biology
Bernstein, BradleyEpigenetic mechanisms in mammalian development
Bischoff, JoyceEndothelial Progenitors in Health and Disease
Blacklow, StephenBiochemistry of transmembrane receptors and signaling
Blackwell, T. KeithAging, Stress Defenses, and Developmental Gene Regulation in C. elegans
Blenis, JohnMolecular Biology of Cell Growth Regulation and Transformation
Blower, MichaelMicrotubule associated RNAs during mitosis
Blumberg, RichardT Cell-Epithelial Cell Interactions in Mucosal Community
Bonni, AzadIntracellular signaling mechanisms in brain development and disease
Brenner, MichaelInnate - Adaptive Immunity and Autoimmunity
Brown, Dennis Polarity and Trafficking of Membrane Proteins in Epithelial Cells
Brugge, Joan Signal transduction in normal and transformed cells
Bulyk, MarthaTranscriptional Regulatory Network Analyses
Buratowski, SteveBiochemical and Genetic Analysis of Eukaryotic Gene Expression
Burns, Caroline Cardiovascular stem cell biology
Camargo, FernandoStem cells and organ size control
Campbell, JamesTissue-specific lymphocyte homing and diversity
Cantley, LewisSignal Transduction
Cantor, Alan Transcription factors in hematopoiesis and leukemogenesis
Carroll, MichaelGenetic Models of Human Disease
Cepko, ConnieMolecular genetics of neural development and gene therapy to prevent blindness
Chan, JoanneDissection of angiogenic signaling in zebrafish
Chien, KennethCardiovascular Stem Cells in Development and Disease
Chou, JamesProtein NMR Spectroscopy of Membrane Protein
Chowdhury, DipanjanDownregulating DNA Repair: Phosphatases & MicroRNAs
Church, GeorgeGenome Structure
Cichowski, KarenCombining genetic and biochemical approaches to dissect tumor suppressor gene function
Clapham, DavidNew Biology through Physics: Molecular Discoveries with Light
Clardy, JonBiologically active small molecules
Coen, DonaldMolecular Genetics of Herpes Viruses
Cohen, DavidMechanisms of hepatic cholesterol elimination
Colaiácovo, Monica Mechanisms underlying accurate meiotic chromosome segregation
Corfas, GabrielMolecular Basis of Neuron Glia Interactions
Cowan, ChadStem Cells and Developmental biology
D’Amore, Patricia Regulation of Vascular Development and Pathology
D’Andrea, Alan Genomic instability and cancer susceptibility
Daley, GeorgeStem cells in disease and development
Daly, MarkGenetics of common human disease
Danial, NikaIntegration of Cellular Metabolism and Apoptosis
Danuser, Gaudenz Mechanochemical regulation of cytoskeleton dynamics
Datta, SandeepFunctional Characterization of Neural Circuits
de Bakker, Paul Genetic basis of human complex diseases
De Jager, Philip Human genetics of neuroinflammatory and neurodegenerative disorders
DeCaprio, JamesCellular transformation by SV40
DePace, Angela Systems Biology Research
Donahoe, PatriciaDevelopmental Biology / Genetics (congenital anomalies, cancer)
Dove, SimonThe regulation of gene expression in pathogenic bacteria
Drapkin, RonnyModeling ovarian cancer pathogenesis and early detection
Drummond, IainGenetic analysis of zebrafish kidney organogenesis
Dulac, CatherineMolecular and Development Neurobiology
Dymecki, SusanDevelopmental Neurobiology and Genetics
Dyson, NicholasControl of Cell Proliferation by RB/E2F
Ebert, BenjaminResearch in hematology and oncology
Eck, MichaelStructure Biology of Cytoplasmic Signal Transduction
Eggan, KevinMechanisms of Epigenetic Reprogramming
Elion, ElaineMolecular Mechanisms of Signal Transduction
Elledge, StephenCell Cycle Control and Genomic Integrity
Engelman, Alan Retroviral DNA Integration
Engle, ElizabethGenetic disorders of axon growth and guidance
Evans, David Primate lentiviral immunology and pathogenesis
Extavour, CassandraComparative and evolutionary invertebrate developmental biology
Farzan, MichaelHIV-1 and Other Viruses
Feany, MelGenetics of neurodegenerative disease
Finley, DanielThe ubiquitin-proteasome pathway
Fisher, DavidEukaryotic survival decisions
Flanagan, JohnCell-cell signaling in neural development
Fleming, MarkMolecular genetics of erythroid iron metabolism
Fontana, Walter Systems Biology Research
Francis, NicoleBiochemistry of Epigenetics
Frank, DavidIntracellular signaling pathways in the regulation of cell growth and differentiation
Freeman, Michael Growth factors and signal transduction
Garcia-Cardeña, Guillermo Control of Endothelial cell fate and vascular development by fluid mechanical forces
Garraway, LeviIntegrated and functional genomic studies of human cancer
Gaudet, SuzanneSystems biology of mammalian cell fate decisions
Gehrke, LeeRNA Structure, RNA-protein Interactions, and Translation-level Gene Regulation in RNA Viruses
Gilmore, Michael Molecular biology multi-drug resistant pathogens
Gimbrone, MichaelTopics in Vascular Biology
Gimelbrant, AlexanderEpigenomics of allele-specific expression.
Goessling, WolframLiver development, regeneration and carcinogenesis
Golan, DavidRegulation of Membrane Protein and Lipid Dynamics: Molecular Mechanisms and Biological Implications.
Goldberg, Alfred Mechanism and Function of Intracellular Protein Turnover
Goldberg, Marcia Pathogen-host interactions
Goodrich, LisaMolecular genetic dissection of auditory circuit assembly and inner ear morphogenesis
Goodyear, Laurie Effects of diabetes, exercise, and skeletal muscle metabolism
Gray, NathanaelFunctional small molecules for biological discovery
Greenberg, MichaelBiochemical Mechanisms Controlling Cell Growth and Differentiation
Gregory, RichardMechanisms of RNAi in stem cells
Gu, ChenghuaThe molecular mechanisms of how neural and vascular networks are coordinately developed
Gusella, James Molecular Genetics of Inherited Disorders
Gussoni, Emanuela Muscle stem cell commitment and differentiation
Gygi, StevenMass Spectrometry and Proteomics
Haber, Daniel Characterization of molecular targets of cancer therapy
Hahn, WilliamMolecular approaches to cell immortalization and transformation
Haigis, Kevin Ras signaling and colon cancer
Haigis, Marcia Mitochondria in aging and metabolism
Harper, J. WadeMechanism and biology of ubiquitin-like protein conjugation cascades
Harris, Matthew Genetic basis of skeletal development and evolution
Harrison, StephenStructure of Viruses, Viral Proteins, Receptors, Transcription Factors
He, XiMolecular mechanism of signal transduction
Heiman, Maxwell Cell Shape
Henske, Elizabeth Tuberous sclerosis and LAM: Pathogenic Mechanisms
Higgins, Darren Molecular Determinants of Intracellular Bacterial Pathogenesis
Higgins, Jonathan Mitotic kinases, chromatin and chromosome segregation
Hirschhorn, Joel Human genetics, Genomics and Complex Traits
Hochedlinger, KonradEmbryonic stem cells, Nuclear Transfer, Cancer, Reprogramming
Hochschild, AnnGene Regulation of Prokaryotes
Hock, HannoTranscriptional control of hematopoiesis and leukemia
Hogle, James X-Ray Crystallographic Studies of Viruses and Proteins
Howley, PeterViral Pathogenic and Tranformation Mechanisms
Hsu, VictorBasic and applied mechanisms of intracellular transport
Hung, DeborahChemical genetics approach to bacterial pathogenesis
Hunter, CraigGenetics and Development
Hur, SunInnate immunity against RNA viruses
Husson, RobertMycobacterial signal transduction and transcription regulation
Iacomini, JohnInduction of Immunological Tolerance by Gene Therapy
Ingber, DonResearch in Integrin Signaling, Cytoskeleton, and Control of Angiogenesis
Italiano, JosephCytoskeletal mechanics of blood platelet production
Jackson-Grusby, LaurieEpigenetic regulation in development and disease
Jain, Rakesh Tumor microenvironment, Angiogenesis and Metastasis: from Bench-to-bedside-to-Biomarkers
Janne, PasiTranslational research on kinase inhibitors
Jensen, FrancesAge-Dependent Mechanisms of Perinatal Brain Injury
Johnson, WelkinMolecular Biology and Evolution of Retroviruses
Joung, J. KeithMolecular recognition and protein engineering
Kagan, JonathanToll-like Receptors and Innate Immunity
Kahn, C. RonaldCellular and Molecular Aspects of Insulin Action
Kahne, Daniel Mechanisms of action of antibiotics
Kalluri, RaghuMatrix biology, cell-matrix interactions in health and disease
Kaplan, JoshuaGenetic analysis of synaptic transmission
Karnoub, Antoine Epithelial:stromal interactions in the formation and progression of carcinomas
Kasper, DennisBacterial / Host Interactions in symbiosis and pathogenesis
Kazlauskas, AndriusMolecular basis of human disease
Khosravi-Far, RoyaSignal transduction pathways involved in cellular proliferation and apoptosis
Kieff, ElliottMolecular biology of Epstein Barr Virus infection and transformation of B Lymphocytes
Kim, CarlaLung stem cell biology and cancer
King, RandyChemical Approaches to Cell Division and Cancer
Kingston, RobertMolecular Mechanisms of Transcription Regulation in Mammals
Kirchhausen, TomasReceptor-Mediated Endocytosis
Kirschner, MarcCell Morphogenesis and Regulation
Klagsbrun, Michael Growth Factor Structure and Function
Knipe, DavidMolecular Biology of Herpes Viruses
Kolter, RobertoMolecular Biology of Bacterial Interactions
Kontaridis, MariaSignal Transduction and Phosphorylation in Heart Disease
Kourembanas, Stella Molecular basis of pulmonary hypertension, hypoxia, inflammation, and stem cell biology
Kreidberg, JordanSignaling networks in development and disease
Kucherlapati, RajuGenetics and genomics of human disease
Kulkarni, Rohit Stem cells, islet cell function, growth and development
Kunkel, LouisNeurogenetics of Disease
Kupper, ThomasSkin Immunology T cell Trafficking Lymphoma
Kuroda, MitziMolecular genetics of chromosome organization and gene expression
Kwiatkowski, DavidHuman, molecular and mouse genetics
Lahav, Galit Systems Biology Research
Langenau, David Self-Renewal and Cancer
Lassar, AndrewRegeneration of cartilage and skeletal muscle
Lee, Charles Studying human diseases through structural genomic variation
Lee, Jeannie Mechanism of X-inactivation in Mammals
Lencer, WayneBacterial toxin entry and immunoglobulin transport in mucosal epithelial cells
Lesser, CammieModeling mechanisms of bacterial pathogenesis
Letai, AnthonyTargeting apoptosis regulation in cancer
Letvin, NormanImmunopathogenesis of Viral Diseases
Levy, Bruce Resolution of lung inflammation and injury
Levy, Ofer Translational immunology in immunocompromised hosts
Li, ZheDevelopmental oncobiology and cancer stem cells
Liao, RonglihCardiac repair and regeneration
Liberles, StephenMolecular Biology of Instinctive Animal Behavior
Lieberman, JudyCytotoxic T Lymphocytes
Livingston, DavidMolecular biology and genetics of Cancer
Look, A. ThomasGenetic models of Leukemogenesis
Loparo, Joseph Single-molecule studies of DNA repair
Lory, StephenHost Pathogen interactions
Loscalzo, JosephEndothelial cell, nitric oxide, proteomic redox regulation
Losick, Richard Microbial Development
Lu, Kun PingCell Growth Regulation, Telomere Maintenance, cancer and Alzheimer's disease
Luo, HongboCell signaling in innate immunity
Maas, RichardGenetic regulation of organogenesis and organ regeneration
Mably, John Models of cardiac development and disease
MacDonald, MarcyMolecular Genetic Approaches to Human Disease Mechanisms
Macklis, JeffreyNeo-Cortical Development and Cellular Transplantation
MacRae, CalumCardiovascular Biology in Human and Zebrafish
Majzoub, JosephHypothalamic gene function and regulation
Malley, Richard Acquired and innate immunity to pneumococci
Mango, SusanMolecular genetics of organ development
Marasco, WaynePrinciples/Practices of Developing Human Antibody Therapies
Marto, JarrodQuantitative proteomics of cancer progression
Mayadas, TanyaPhagocyte-endothelial cell responses in inflammation
McAllister, Sandra Molecular and cellular regulators of cancer progression
McCarroll, StevenHuman genome structural and regulatory variation
McClatchey, AndreaMembrane:cytoskeleton interface in morphogenesis and tumorigenesis/metastasis.
McKeon, FrankThe Structure of the Nucleus and the Dynamics of Nuclear Transport
McMahon, AndrewVertebrate Development
Megason, Sean Systems Biology Research
Meissner, AlexanderEpigenetic modifications and cellular identity
Mekalanos, JohnMolecular Mechanisms in Pathogenesis
Melton, DouglasVertebrate Development Biology
Meselson, Matthew Biology of Aging
Meyerson, MatthewBiology and genetics of human cancers
Michel, Thomas Cardiovascular signal transduction
Mitchell, RichardMechanisms of acute and chronic allograft rejection
Mitchison, Timothy Cytoskeletal Dynamics
Moazed, DaneshGene Silencing and Chromosome Structure
Mootha, Vamsi Systems Biology Research
Mora, Jorge Rodrigo Tissue-specific leukocyte trafficking in health and disease
Morton, CynthiaResearch in Molecular Cytogenetics
Moses, MarshaBiochemical and molecular regulation of vascular growth
Mostoslavsky, RaulChromatin Dynamics in metabolism and DNA repair
Mulligan, RichardDevelopment Applications of Mammalian Vectors
Münger, Karl Viral Oncoproteins as Probes to Study the Regulation of Cell Growth and Differentiation
Näär, Anders Molecular mechanisms of transcriptional control
Newton-Cheh, ChristopherComplex trait genetics of blood pressure and QT interval variation
North, Trista Blood stem cell development and regeneration
Novina, CarlMechanisms and Applications of Mammalian RNA interference
Oettinger, MarjorieMolecular Biology of V(D)J Recombination
Olsen, BjornMolecular Biology of Extracellular Matrix
Orkin, StuartHuman Molecular Genetics
Pandolfi, Pier PaoloThe molecular genetics of human cancer
Park, PeterComputational Genomics
Paw, BarryGenetics of Blood Development
Pellman, DavidThe mechanics and regulation of mitosis
Perelman, Lev Bioimaging and Optical Spectroscopy: Detection of Early Disease with Light
Perrimon, NorbertGenetic analysis of growth and homeostasis
Pier, GeraldBacterial pathogenesis and vaccine development
Pollak, Martin Kidney disease, genetics, cytoskeleton
Polyak, KorneliaMolecular Basis of Breast Cancer Initiation and Progression
Pu, William Transcriptional and Epigenetic Regulation of Heart Development. Cardiac Regeneration and Cardiac Stem Cells
Puigserver, PereNutrient Sensing and Metabolic Control
Rabkin, SamuelHSV Vectors for Cancer Therapy
Rajagopal, Jayaraj Lung Regeneration and Lung Disease
Rapoport, TomProtein Transport Across the Endoplasmic Reticulum Membrane
Reck-Peterson, SamaraMolecular Mechanism of Microtubule-Based Motility
Reich, DavidApplying population genetics to find disease genes
Richardson, CharlesStructure and Replication of DNA
Rinn, JohnEpigenetic Regulation by Large Non-coding RNA
Roberts, Charles Chromatin and Cancer
Roberts, Thomas Control of Gene Expression Tumorgenesis and Differentiation
Rosen, Evan Molecular Approaches to Metabolism and Energy Balance
Rosen, Vicki BMP signaling in organogenesis
Rosenberg, Paul Glutamate transporters, cell death, sleep/wake regulation
Rosenzweig, AnthonySignal transduction in heart failure and atherosclerosis
Rossi, DerrickHematopoietic stem cell biology and aging
Rubin, Eric Bacterial genetics of tuberculosis and tularemia
Rubin, Lee Stem Cells and Neurodegenerative Disease
Ruderman, JoanRegulation of Cell Cycle
Rudner, DavidMolecular Mechanisms in Bacterial Differentiation
Ruvkun, GaryMolecular Genetics of Development
Sagar, ManishPathogenesis of HIV-1 transmission
Sahin, MustafaCellular Mechanism(s) of Axon Guidance
Salic, AdrianMechanisms of vertebrate Hedgehog signaling
Sanes, JoshuaSynapse Formation
Saper, CliffordHypothalamic circuitry controlling sleep and circadian rhythms
Scadden, David Hematopoietic stem cells and their niche
Schier, AlexanderDevelopmental Genetics and Neurobiology
Schwarz, ThomasGenetics of Neuronal Cell Biology
Scully, RalphRecombination functions of the BRCA genes
Seed, BrianMolecular Biology of Signal Transduction
Segal, RosalindNeurotrophic factors in development: Functions and mechanisms of action
Seidman, Christine Molecular genetics basis of human disease, particularly cardiovascular pathogenesis
Seidman, Jonathan Inherited human disorders
Selkoe, DennisMolecular Mechanisms of Neurodegeneration in Alzheimer's and Parkinsons Diseases
Serhan, CharlesChemical mediators in inflammation and resolution
Shah, Jagesh Systems Biology Research
Sharpe, ArleneRegulation of T-cell Mediated Immune Response
Sheen, JenMolecular Mechanisms of Plant Signal Transduction
Shi, Yang Transcriptional control in differentiation/development & tumorigenesis
Shi, Yujiang Geno Epigenomics and Chromatin Systems Biology
Shih, WilliamBiomolecular nanotechnology
Shivdasani, Ramesh Cancer and development, thrombopoiesis, intestinal development
Shoelson, StevenSignal transduction and related molecular pathophysiology
Sicinski, Peter Cell cycle proteins in development and cancer
Silver, Pamela Systems Biology Research
Sinclair, DavidMolecular mechanisms of aging and age related diseases
Slaugenhaupt, SusanGenetics of human disease
Snapper, ScottSignal Transduction, Host-Microbial Interactions and Immunology
Sorger, PeterSystems biology of mammalian signal transduction
Spiegelman, BruceMechanisms of Mammalian Cell Differentiation and Gene Expression
Springer, Michael Systems Biology Research
Springer, Timothy Molecular Basis of cell adhesion and migration
Starnbach, MichaelT-Lymphocyte Responses to Bacterial Pathogens
Struhl, KevinEukaryotic Gene Regulation
Sunyaev, Shamil Computational analysis of sequence variation and divergence
Szostak, JackStructure and Activities of Ribozymes
Tabin, Cliff Vertebrate Pattern Formation
Toker, AlexSignaling Pathways in Cancer Cell Biology
Van Vactor, DavidNeuronal Pathfinding and Synaptogenesis
Vasudevan, Shobha microRNA functions in cancers and quiescence
Verdine, Gregory Approaches Toward Understanding and Treating Human Disease
Vidal, Marc Functional genomics and proteomics
von Andrian, UlrichMolecular Mechanisms of Leukocyte Trafficking
Wagers, AmyBiology and function of tissue-specific stem cells
Wagner, Gerhard NMR spectroscopy of proteins and metabolites
Waldor, Matthew Biology and virulence of enteric pathogens
Walensky, LorenTargeting deregulated apoptotic and transcriptional pathways in cancer
Walker, SuzanneChemical biology, enzymology, antibiotics, glycosyltransferases, inhibitors
Walsh, Christopher A. Molecular Genetics of Cerebral Cortical Development
Walter, JohannesMaintenance of genome stability in S phase
Walz, ThomasElectron microscopic structure determination
Wang, Da-Zhi Cardiovascular development and disease, muscle biology
Wang, FredMolecular Biology of Epstein-Barr Infection
Warman, MatthewDevelopment and homeostasis of the skeleton
Watnick, PaulaGenetics of bacterial adhesion and pathogenesis
Wei, WenyiCell cycle, Ubiquitination and protein degradation, cancer research
Weinstock, David Cancer genetics and DNA repair
Weissleder, RalphBioimaging, nanomaterials and systems biology
Wessels, MichaelMolecular pathogenesis of streptococcal infection
Wessling-Resnick, MarianneRegulation of the Cellular uptake of Macromolecular Nutrients
Whelan, SeanTranscriptional Regulation of Viral and Mammalian Genes
Whetstine, JohnathanImpact of Epigenetics on Cellular Homeostasis
White, Kristin Genetic control of apoptosis in Drosophila
White, Morris Molecular and Cellular Mechanisms of Insulin Action
Whitman, MalcolmSignal Transduction During Early Development
Williams, DavidBiology of hematopoietic stem cells
Winston, FredGene Expression in Yeast
Wirth, DyannMolecular Biology of Parasites
Wolfe, MichaelBiochemistry and biology of neurodegenerative diseases
Wong, Wesley Single-molecule Biophysics and Force Spectroscopy
Wu, Ting (C.-ting) Epigenetics, genetics, gene regulation, ultraconserved elements
Wucherpfennig, KaiMolecular mechanisms of T cell activation
Xavier, Ramnik Signaling networks in immunity, Functional analysis of genetic variants associated with autoimmune disease
Yan, CatherineStem cells, Cancer, and Hematological Disorders
Yang, PriscillaChemistry and biology of Host-virus interactions
Yankner, BruceThe Neurobiology of Alzheimer's disease and related neurodegenerative disorders
Yuan, JunyingMechanisms of Programmed Cell Death
Yusufzai, Timur Chromatin and DNA Dynamics
Zetter, BruceMechanisms of Tumor Metastasis
Zhao, JeanKinase signaling in cancer
Zhou, Jing Centrosomes, Cilia, Cysts and Diseases
Zhou, Qiao (Joe) Adult mammalian regeneration
Zon, LeonardDevelopmental Biology of Hematopoiesis
Zou, LeeDNA damage responses and genomic stability