Herpes Encephalitis: T2-weighted MR -- Slice #15
Tour 1: Next/Previous/Start: The following section summarizes the brain damage in this case, and links each structure mentioned to its entry in the Atlas of the normal brain. Move through the dataset (use the buttons at left) to view each of the structures mentioned.

Abnormally high signal extends from the right temporal tip medially to involve the hippocampus, amygdala, and the parahippocampal gyrus, superiorly to involve orbital frontal gyri, the straight gyrus, and the cingulate gyrus; and posteriorly and superiorly to involve the insula, the anterior bank of the superior temporal gyrus, and the posterior hippocampus as it blends into the column of the fornix. Medially, the lesion displays evidence of tracking along an anatomically restricted course, as it borders the posterior genu of the internal capsule. The greatest superior extent of the lesion involves the posterior portion of the medial nucleus of the thalamus, a structure known to have anatomic connections with amygdala and other limbic structures (Nauta WJH. Neural association of the amygdaloid complex in the monkey. Brain 1962; 85:505-520). HSV has also damaged the intralaminar thalamic nuclei, structures known to have extensive connections with the limbic system (Van Landingham KE and Lothman EW. Self-sustaining limbic status epilepticus. Neurology 1991;41:1942-9.)

[Home][Help][Clinical][Tour 1] Slice 15
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Keith A. Johnson (keith@bwh.harvard.edu), J. Alex Becker (jabecker@mit.edu)