JPNM Physics

Early History of Collimated 511 keV imaging

Document created May 29, 1996


Fluorine imaging began in the 1960s with the introduction of bone scanning using F-18 as the fluoride ion . (Blau 1962) . The instrument of choice was the dual-head rectilinear scanner, preferably the whole body version. Anger used his positron camera in 1965 to do F-18 bone scanning (Van Dyke et al).

Bone scanning with Sr-85 (514 keV, 64.84 d) and Sr-87m (388 keV, 2.80 h) also presented a similar high energy imaging challenge (Fleming 1961, Charkes 1969).

These isotopes were not well suited for use with the gamma cameras of this era and the rectilinear scanner was the preferred instrument.

The introduction of Tc-99m phosphate imaging changed all that in the early 1970s (Subramanian, 1971).


Robert E. Ziimmerman, MSEE, zimmer@bwh.harvard.edu