Case 16
Clinical History:
A 29 year-old woman noted an upper outer quadrant mass in her left breast in June of 1986. In July she had a positive pregnancy test; at her first obstetric appointment in September, she was referred for a surgical opinion of the breast mass. After an unsuccessful attempt at needle biopsy, she underwent excisional biopsy on 11/4/86, which revealed an infiltrating ductal carcinoma with tumor at the margins of resection; 5/17 axillary lymph nodes were positive for tumor. Flow cytometry on the tumor was reported as aneuploid, with high S phase, indicating increased risk of relapse with poor survival probability. Estrogen and progesterone receptor levels were < 3 and 5 fmol/mg, respectively. At the time, the patient was 23 weeks pregnant.
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J. Anthony Parker, MD PhD, jap@nucmed.bih.harvard.edu
